Product Focus

Three new products available for trainers this spring 2023

PAVESCO - TWYDIL® ARTRIDAY

NEW feed supplement for joints from TWYDIL®, Switzerland.

Since MSM has been registered as a controlled substance, we decided to launch on the equine market a product that can be used daily and long term.

Following our recent scientific investigations, it appears that the combination of chondroïtin, glucosamine, pro-anthocyanin and ASU brings an active and efficient support on the cartilage health and its functionality. 

ASU means « avocado and soybean unsaponifiable fatty acids ». This extract is particularly efficient for the stabilisation of the cartilage extra-cellular matrix, bringing a noticeable preventive effect. The combination of these ingredients have an effect on all parts of the joints: cartilage, synovial fluid and membrane. The pro-anthocyanin fraction has a powerful anti-oxidant property with a high tropism for joints, so breaking the vicious circle conducting to lameness.

Horses show an improvement of their general suppleness and of their stride. The well-being is also taken into consideration because training is better tolerated. 

50g daily for 30 days minimum is recommended to observe an improvement. It may be needed to continue for a longer period in sensitive horses.

The product is available in 1.5 kg pails.

For more information visit: www.twydil.com

NAF Five Star Metazone 

By Dr Andy Richardson BVSc CertAVP(ESM) MRCVS, Veterinary Director at NAF

Whatever the challenge, keep your yard ‘in the zone’ with NEW NAF Five Star Metazone. 

Metazone has been formulated by the Veterinary and Nutrition experts at NAF and is an innovative, evidence based nutraceutical that targets the support of natural anti-inflammatory pathways in all racehorses. The synergistic blend of plant based phytochemicals that make up this product support these pathways wherever they are needed in the body - whether that be for joints, hooves, tendons, ligaments, muscles or skin. The unique herbal complex of Metazone works in synergy wherever those triggers occur within the system, to ensure we maintain freedom from discomfort. Maintaining optimum comfort ensures racehorse welfare and provides an optimal environment for recovery and maximising athletic potential.

Unwanted or excessive inflammation is a major issue for the well-being and performance of horses in training and a major cause of lost training days and missed races. Metazone is the culmination of many years of research and knowledge gathered by the scientific team at NAF on how plant based phytochemicals can positively influence the body.

Formulated specifically to manage, relieve and control, Metazone provides nutritional support for common issues that may interrupt a training schedule. Metazone supports a horse’s natural anti-inflammatory responses, which are often under maximum stress when in training, helping them to stay sound through periods of repeated, strenuous exercise. The product is suitable when a short term boost is needed but may also be used for long term daily administration when comfort is key. The natural formula is gut kind and designed to work effectively without compromising gut health. It can be fed alongside any other NAF product that will support underlying structures as required.

Independently trialled, Metazone has been robustly trialled by equine researchers at The Royal Agricultural University, Cirencester in a blinded, cross-over designed trial, and assessed by a panel of external vets. Real results research also includes trials with leading trainers, who have all seen the benefit of getting their horses ‘in the Metazone’. 

Metazone is available as a fast-acting liquid, in an instant use syringe and as palatable powder. The liquid comes in 5L and 1L sizes with the syringes available as 3 x 30ml and the powder is in a 1.2kg tub. 

For more information on pricing and the product, contact NAF’s Racing Manager Sammy Martin on 07980 922041 or smartin@naf-uk.com. 

Plusvital - Neutragast

Plusvital Neutragast is now available in pellets.

Ideal for fussy eaters, Neutragast Pellets promote gastrointestinal health in convenient & palatable soy protein base pellet form.

Using research proven ingredients to promote digestive performance the pellets contain key ingredients boswellia extract, calcified seaweed, saccharomyces cerevisiae and provides a source of B vitamins to help with food metabolism.

Boswellia extract (Terepenes and Boswellic acids) have been shown to have several beneficial effects including anti-inflammatory and analgesic properties. Boswellia compounds have been shown to be of benefit in cases of intestinal inflammation. This is achieved through modulation of the inflammatory cell (leukocyte) response.

Calcified seaweed has been reported to have a positive effect on buffering of pH in equine stomachs. Presented in the form of Lithothamnium Calcareum this acts as a safeguard against excess acid within the stomach.

Additionally Plusvital Neutragast Pellets contain the amino acid Threonine which is one of the main amino acid components of the protein mucin. Mucin forms a gel-like structure which makes up the mucosal barrier that protects the stomach wall against its own acidic secretions.

Saccharomyces cerevisiae (active yeast) is a probiotic which promotes intestinal health through multiple pathways including increased fibre digestion.

As it is a pellet supplement it works well with pelleted feed or straight feed concentrates and can be used as part of a daily routine.

For more information visit: www.plusvital.com

Nutrition and the new science of the "Gut-Brain connection"

Article by Scott Anderson

Trainers are always looking to gain an edge in performance. But what about their mental state? Are they jittery, distracted or disinterested? No matter how strong the horses, their heads must be in the game to succeed.

Surprisingly, much of that mental attitude is driven by gut health, which in turn depends on the collection of microbes that live there: the microbiota. In a horse, the microbiota is a tightly packed community of about 100 trillion microbes, composed of bacteria, archaea, fungi and protozoa. It colonises the entire GI tract but is largely concentrated in the hindgut, where it works to ferment the prebiotic fibre in forage. The microbial fermentation of fibre into fatty acids produces 70% of the animal’s energy requirements and without it, the horse couldn’t get sufficient energy from simple forage. Intriguingly, byproducts of that fermentation can affect the brain. 

It is easy to be sceptical about this gut-brain connection, but over the last decade, research has made it clear that gut microbes have an outsized influence on mood and behaviour. Microbes that improve mental state are called psychobiotics, and they may completely change the way you train and manage your horses. A horse’s health – and consequently its performance – starts in the gut.

Inflammation

When the microbiota is unbalanced by stress, diet or sickness, it is said to be dysbiotic. It loses diversity, and a handful of bacterial species compete for domination. Without the pushback of a diverse population, even beneficial bacteria can become pathogenic. Surprisingly, that can affect the brain. Multiple studies in various animal models have shown that transmitting faecal matter from one animal to another also transmits their mood. This demonstrates that a dysbiotic microbiota can reliably cause mental issues including anxiety and depression, thereby affecting performance. 

An important function of the microbiota is to fight off pathogens by outcompeting, starving or killing them. However, a dysbiotic microbiota is less diligent and may permit pathogens to damage the gut lining. A degraded gut lining can leak, allowing bacteria and toxins into the bloodstream. The heart then unwittingly pumps them to every organ in the body, including the brain. This makes the gut the primary source of infection in the body, which explains why 80% of the immune system is located around the intestines. Over time, a leaky gut can lead to chronic systemic inflammation, which weakens the blood-brain barrier and interferes with memory, cognition and mood. 

Inflammation is a major component of the gut-brain connection, but not the only one.

Neurotransmitters and hormones

Horses and humans use neurotransmitters to communicate between nerve cells. Brains and their attendant nerve bundles constitute a sophisticated network, which makes it somewhat alarming that microbes also produce neurotransmitters. Microbes use neurotransmitters to converse with each other, but also to converse with their host. The entire gut is enmeshed in nerve cells that are gathered up into the vagus nerve that travels to the brain. Microbial neurotransmitters including serotonin and dopamine thus allow certain microbes to communicate directly with the brain via the vagus nerve. We know this happens with specific bacteria, including Lactobacillus species, because when the vagus is severed, their psychobiotic effects disappear. 

As well as neurotransmitters, hormones are involved in gut-brain communications. The hypothalamus-pituitary-adrenal (HPA) axis controls the stress response in animals. The hypothalamus is located low in the brain and responds to stressors – such as a lurking predator – by producing hormones that stimulate the neighbouring pituitary, which then triggers the adrenal gland to produce cortisol, the stress hormone. Cortisol acts as a threat warning and causes the horse to ramp up glucose production, supplying the energy needed to escape a predator. This is the same hormonal circuit that trainers exploit for racing.

The HPA axis produces cortisol in response to stress. Cortisol inhibits the immune system, which in combination with a leaky gut allows pathogens to enter the bloodstream. Susequent systemic inflammation and vagal feedback lead to stereotypies.

The production of these hormones redirects energy to the heart, lungs and muscles at the expense of the immune system. From an evolutionary point of view, the tradeoff makes sense: first escape the predator and deal with infections later. After the danger has passed, cortisol causes the HPA to return to normal – the calm after the storm. 

However, continued stress disrupts that cycle, causing anxiety and diminishing the brain’s ability to store memories. This can dramatically interfere with training. Stress can also induce the release of norepinephrine, which promotes the growth of pathogenic bacteria including Campylobacter jejuni, Listeria, Helicobacter pylori, and Salmonella. Prolonged high cortisol levels can increase gut leakiness, potentially leading to infection and further compounding the situation. In the long term, continued stress leads to systemic inflammation, which is a precursor to problematic behaviours.

Short-chain fatty acids

When microbes consume proteins and fibre, they break them down into their constituent molecules, such as amino acids, fatty acids and sugars. These are the metabolites of the microbes. As well as neurotransmitters and hormones, the gut-brain conversation is mediated by metabolites like butyrate, an important short-chain fatty acid which plays multiple roles in the body. 

In the gut, butyrate serves as a preferred nutrient for the cell lining. It encourages the differentiation of stem cells to replenish gut cells that are routinely sloughed off or damaged. It plays an important role in the production of mucus – an essential part of gut protection – which coats the gut from mouth to anus. In the muscles, butyrate boosts the growth of skeletal muscle, crucial to athletic performance, as well as inducing the production of glucose, the primary muscle fuel. One-quarter of systemic glucose is driven by butyrate. In its gut-brain role, butyrate passes through the blood-brain barrier, where it nourishes and enhances the growth of new brain cells. 

These factors make butyrate a star player in the gut-brain connection. They also highlight the benefits of prebiotic fibre, especially when high-energy, low-fibre feeds are provided.

Starting a microbiota

We’ve explored the major pathways of the gut-brain connection: inflammation, neurotransmitters, hormones and fatty acids. Some of these pathways are at odds with each other. How does such a complicated system come together?

As mentioned, the microbiota is an animal’s first line of defence against pathogens, attacking and killing them often before the immune system is even aware of them. That means a healthy microbiota is an essential part of the immune system. However, the immune system is designed to attack foreign cells, which includes bacteria. For the microbiota to survive, the immune system must therefore learn to accept beneficial microbes. This lesson in tolerance needs to take place early in the foal’s development, or its immune system may forever fight its microbiota.

There are multiple ways nature ensures that foals get a good start on a microbiota that can peacefully coexist with the immune system. The first contribution to a protective microbiota comes from vaginal secretions that coat the foal during birth. After birth, microbes are included in the mare’s milk. These microbes are specially curated from the mare’s gut and transported to the milk glands by the lymphatic system. Mare’s milk also includes immune factors including immunoglobulins that help the foal to distinguish between microbial friends and foes. An additional way to enhance the microbiota is through coprophagia, the consumption of manure. Far from an aberration, foals eat their mother’s manure to buttress their microbiota. 

Microbes affect the growth and shape of neurons in various brain sites as the foal develops – a remarkable illustration of the importance of a healthy early gut microbiota. 

The cooperation between the immune system and the microbiota is inevitably complex. Certain commensal bacteria, including Clostridiales and Verrucomicrobia, may be able to pacify the immune system, thus inhibiting inflammation. This is a case where microbes manage the immune system, not the other way around. These convoluted immune-microbial interactions affect the mental state – and consequently the behaviour – of the horse, starting at birth.

Stereotypies

A 2020 study of 185 performance horses conducted by French researchers Léa Lansade and Núria Mach found that the microbiota, via the gut-brain connection, is more important to performance than genetics. They found that microbial differences contributed significantly to behavioural traits, both good and bad. A diversified and resilient microbiota can help horses better handle stressors including stalling, training, and trailering. A weakened or dysbiotic microbiota contributes to bad behaviours (stereotypies) and poor performance. 

The horses in this study were all carefully managed performance horses, yet the rates of stereotypies were surprisingly high. A kind of anxiety called hypervigilance was observed in three-quarters of the horses, and almost half displayed aggressive behaviour like kicking or biting. 

The study found that oral stereotypies like biting and cribbing were positively correlated with Acinetobacter and Solibacillus bacteria and negatively correlated with Cellulosilyticum and Terrisporobacter. Aggressive behaviour was positively correlated with Pseudomonas and negatively correlated with Anaeroplasma. 

Some of these behaviours can be corrected by certain Lactobacillus and Bacteroides species, making them psychobiotics. That these personality traits are correlated to gut microbes is truly remarkable. 

Intriguingly, the breed of a horse has very little impact on the makeup of its microbiota. Instead, the main contributor to the composition of the microbiota is diet. Feeding and supplements are thus key drivers of the horse’s mental state and performance. 

The gut-brain connection and training

How might the gut-brain connection affect your training practices? Here are some of the unexpected areas where the gut affects the brain and vice-versa:

High-energy feed. Horses evolved to subsist on low-energy, high-fibre forage and thus have the appropriate gut microbes to deal with it. A high-energy diet is absorbed quickly in the gut and can lead to a bloom in lactic acid-producing bacteria, which can negatively impact the colonic microbiota. High-energy feeds are designed to improve athletic output, but over time, too much grain can make a horse antisocial, anxious and easily spooked. This can damage performance—the very thing it is trying to enhance. Supplementary prebiotics may help to rebalance the microbiota on a high-starch regimen.

Changing feed regimens quickly. When you change feed, certain microbes will benefit, and others will suffer. If you do this too quickly, the microbiota can become unbalanced or dysbiotic. Slowly introducing new feeds helps to prevent overgrowth and allows a balanced collection of microbes to acclimate to a new regimen. 

Stress. Training, travelling and racing all contribute to stress in the horse. A balanced microbiota is resilient and can tolerate moderate amounts of stress. However, excessive stress can lead, via the HPA axis, to a leaky gut. Over time, it can result in systemic inflammation, stereotypies and poor performance.

Overuse of antibiotics. Antibiotics are lifesavers but are not without side effects. Oral antibiotics can kill beneficial gut microbes. This can lead to diarrhoea, adversely affecting performance. The effects of antibiotics on the microbiota can last for weeks and may contribute to depression and anxiety. 

Exercise and training. Exercise has a beneficial effect on the gut microbiota, up to a point. But too much exercise can promote gut permeability and inflammation, partly due to a lack of blood flow to the gut and consequent leakiness of the intestinal lining. Thus, overtraining can lead to depression and reduced performance.

Knowing how training affects the gut and how the gut affects the brain can improve outcomes. With a proper diet including sufficient prebiotic fibre to optimise microbiota health, a poor doer can be turned into a model athlete. 

References

Mach, Núria, Alice Ruet, Allison Clark, David Bars-Cortina, Yuliaxis Ramayo-Caldas, Elisa Crisci, Samuel Pennarun, et al. “Priming for Welfare: Gut Microbiota Is Associated with Equitation Conditions and Behavior in Horse Athletes.” Scientific Reports 10, no. 1 (May 20, 2020): 8311.

Bulmer, Louise S., Jo-Anne Murray, Neil M. Burns, Anna Garber, Francoise Wemelsfelder, Neil R. McEwan, and Peter M. Hastie. “High-Starch Diets Alter Equine Faecal Microbiota and Increase Behavioural Reactivity.” Scientific Reports 9, no. 1 (December 9, 2019): 18621. https://doi.org/10.1038/s41598-019-54039-8.

Lindenberg, F., L. Krych, W. Kot, J. Fielden, H. Frøkiær, G. van Galen, D. S. Nielsen, and A. K. Hansen. “Development of the Equine Gut Microbiota.” Scientific Reports 9, no. 1 (October 8, 2019): 14427.

Lindenberg, F., L. Krych, J. Fielden, W. Kot, H. Frøkiær, G. van Galen, D. S. Nielsen, and A. K. Hansen. “Expression of Immune Regulatory Genes Correlate with the Abundance of Specific Clostridiales and Verrucomicrobia Species in the Equine Ileum and Cecum.” Scientific Reports 9, no. 1 (September 3, 2019): 12674. 

Daniels, S. P., J. Leng, J. R. Swann, and C. J. Proudman. “Bugs and Drugs: A Systems Biology Approach to Characterising the Effect of Moxidectin on the Horse’s Faecal Microbiome.” Animal Microbiome 2, no. 1 (October 14, 2020): 38.

Which products and services should trainers be using in 2023?

Cavalor - ArtiTech

Low-grade inflammation is common in joints that perform. However, joint inflammation initiates a cascade of catabolic reactions that gradually degrade the cartilage and may result in lameness.

During an extensive research program, Cavalor has designed a multi-ingredient nutraceutical that helps with protecting joints of equine athletes. The effectiveness of Cavalor ArtiTec has been documented by both in vitro and in vivo experiments and the overall efficacy in the treatment of lameness is supported by the results of a clinical pilot study.

The efficacy and especially the synergistic potential of the individual raw materials and botanical ingredients on inflammation, cartilage protection and repair has been studied over 7 years. These findings have led to the final formulation of Cavalor ArtiTec.

Combining botanical ingredients is a widely applied practice to compose effective products. The final result is believed to be of similar or better potency as that of a single herb. The advantage of using suboptimal efficacious dose levels of each botanical ingredient is reducing the risk of potential toxicities associated with the usage of single herbs.

In the follow-up of the results of previous studies, 7 candidate formulations were evaluated (in vitro) to further unlock the mechanism of action of these formulations and their efficacy. The influence on various biomarkers related to joint health and homeostasis were evaluated using primary human chondrocytes isolated from knee joints in various in vitro models. This study has led to the development of the final candidate formulation for evaluation in a combined mechanistic and efficacy horse specific joint inflammation model (Phase III).

In conclusion, Cavalor ArtiTec is a complete multi-ingredient nutraceutical with proven efficacy for optimising joint health in equine athletes. Cavalor ArtiTec delivers everything our equine ‘athletes’ deserve during periods of intense activity and stress. 

For more information contact: Website: www.cavalordirect.co.uk Telephone: +44 1902 213483

Duggan Veterinary - ConfidenceEQ®

Pheromone communication has been at the heart of Duggan Veterinary Supplies expertise for over 40 years, and we are now pleased to announce the launch of the innovative equine appeasing pheromone, ConfidenceEQ®.

A pheromone is a naturally occurring chemical that an animal produces used for intraspecies communication, which means that their presence automatically and predictably affects all members of the same species, regardless of age or gender.

Like many mammals, nursing mares naturally emit a calming pheromone that reassures their newborn foal. When the foal encounters unfamiliar situations and uncharted territory, this pheromone makes the foal feel comfortable, secure, and more self-assured, enabling them to better learn about their surroundings. ConfidenceEQ® is an identical replica of this horse appeasing pheromone. Numerous studies have been conducted since the equine appeasing pheromone was discovered, proving its effectiveness in reducing stress in conditions that occur frequently in horses of all ages.

Donal Duggan is delighted to add ConfidenceEQ® to the Duggan Veterinary Equine armoury, stating: “The ideal time to use ConfidenceEQ® is when you anticipate your horse will be exposed to something new which they may find stressful. ConfidenceEQ® helps reassure horses, helping them focus allowing them to use their own skills to cope with their surroundings and can be used to help build confidence in situations such as: Loading, travelling and recovery after arrival; Environmental changes (new yard, stabling) or competition environment; Social situations (weaning foals, meeting new horses); Dealing with loud noises (large crowds, thunderstorms, fireworks); Breaking young horses and introducing new exercises during training; Farrier, vet, or dental visits.”

Horses in these situations may show signs of stress such as pawing, vocalising, flared nostrils, kicking, lack of concentration, and resistance. These behavioural changes are due to an elevated cortisol level, which when prolonged, also triggers multiple physiological responses like increased heart rate and blood pressure, weakening of the immune system, cribbing, and digestive issues - all of which can develop into significant problems for owners, trainers, and veterinary practitioners.

ConfidenceEQ® is easy and quick to apply. There are no syringes, mixing food, pills or other uncomfortable application methods that can be difficult to administer or add stress to your horse. It takes effect in 30 minutes, lasts 2.5 hours, and can be reapplied as needed.

For more information contact: Email: sales@dugganvet.ie or uksales@dugganvet.com 

Freedom Health - Total Gut Health

Horses actively training and racing commonly struggle with digestive health, problems which manifest most obviously in gastric issues. Additionally, many racehorses experience concurrent hindgut problems less easily recognised. Not eating well, sudden changes in behaviour, resistant and mean attitudes, not fully using the body, and struggling to maintain weight and condition are a few of the problems that can be associated with hindgut health.

It’s important to actively manage the health of the horses’ entire digestive tract to stop the treat-and-repeat cycle and keep your horses in top condition. A healthy gut is a core requirement for a racehorse to perform to its full potential.

Unfortunately, training, travelling, racing, and breeding chronically stress the horse and especially the digestive tract. Management and feeding practices have changed beyond recognition over the last few decades. But the equine digestive tract remains the same, having been accustomed to a low-stress, nomadic lifestyle while consuming a high-fibre, trickle-fed diet. Modern husbandry practices and feeding grain-based feeds, further complicated by competition stresses, can be significant contributors to digestive issues. What, then, can you do for these horses?

Support total digestive health by feeding SUCCEED® Digestive Conditioning Program™ once a day every day. SUCCEED maintains optimal digestive health in athletic horses naturally with science-based, human-food-grade quality, proven ingredients. It serves as an ongoing maintenance program for the health of the entire digestive tract.

Product trials available on a limited basis. Contact Sandra Hughes: shughes@freedomhealthllc.com.

SUCCEED® Digestive Conditioning Program™

The patented and proven SUCCEED formula delivers nutrients the body requires for GI anatomy and function. It provides a variety of benefits including:Oat Oil – specially extracted to preserve polar lipids which support nutrient absorption and bioavailability; Oat Flour – specially processed to preserve ß-glucan, a soluble fibre that provides support for a healthy immune system and a normal, healthy rate of feed transit through the GI tract; Yeast – a combination of a mannan oligosaccharide and a yeast ß-glucan help maintain a healthy, balanced hindgut and natural immunity; Amino Acids – provide fuel for muscles and support production of mucin, a necessary component of the mucus that lubricates and protects the gut lining.

“I have been using SUCCEED, and I couldn’t be happier with the results. You can visually see a big difference in the horses’ condition very quickly. I believe that it is really enabling their digestive systems.”

Richard Hughes, Horse Trainer

For more information visit: Succeed-equine.co.uk or @succeedequine

NAF - Immuforte

Keep the whole yard healthy, and ready to race, with NEW NAF Immuforte. 

The busy racing yard environment presents the perfect storm of challenges for your horses’ immune systems; and any trainer knows when immune challenge hits, training days, performance and results are lost. Keeping them healthy keeps your training regime on track, and ensures the season’s goals remain in sight for every horse on your yard. 

CREDITED TO JESS PHOTOGRAPHY

Regular travel, intense exercise and being stabled in close proximity, often with shared air space, means a daily assault on every racehorse’s natural defences. Add the challenge of frequent new arrivals, particularly young horses, with naïve immune systems, working closely together, and the risk is self-evident. 

Requested by trainers. Formulated by Equine Vets and Registered Nutritionists. Trialled by trainers, riders and professionals in elite equine sport. BETA NOPS accredited, and designed to meet the highest regulatory and quality standards for racing throughout Europe, and beyond. New NAF Immuforte builds on over 30 years of experience at NAF, in innovative evidence-led solutions, to provide targeted immune support for equine athletes. 

Containing a key natural extract proven to boost the equine immune system, Immuforte supports white blood cell numbers and activity, and targets the oxygen load capacity of red blood cells. Uniquely, Immuforte combines the recognised immune support of echinacea with natural antioxidants and adaptogenic botanical extracts, including, rosehip, turmeric, ginkgo and omicha, to regulate cellular responses, and further support the body’s own defence against unwanted attack. 

NAF Immuforte is available as a palatable liquid, in an easy to feed, auto-measured pump dispense liquid. The perfect solution to your yard’s natural defences.

For more information contact: Website: www.naf-equine.eu Telephone: 0800 373 106

Plusvital - Racing Syrup

The globalisation of racing has eroded the margins of success between trainers. High performance is no longer guaranteed based on pedigrees. A study carried out on winning margins in racing suggests that the overall percentage difference between first place and second place  is 0.32%, the difference between first and third was 0.75%. Never before has optimising recovery and nutrition been as important in gaining percentages of improvement which can be the difference between winning and not. 

Days post-race or fast work the body recovers and adapts allowing the horse to become more oxygen efficient and physically stronger. Muscle recovery requires specific vitamins, minerals and amino acids to give the horse the best possible opportunity to maximise its full potential. This vital edge is optimised by correct nutrition. Supporting race horses' mineral and vitamin levels is critical to racing success today. 

Used for 47 years by global racing elite Plusvital Racing Syrup is formulated to provide 30 essential vitamins and minerals exceeding NRC recommendations. Key ingredients facilitate strength and recovery.  

B vitamins are an essential group of vitamins for a horse to perform at its best. The harder they work the higher the requirement for vitamin B is. B vitamins play a vital role in forming red blood cells, responsible for carrying oxygen to muscles allowing the horse to continue galloping at high intensity whilst removing carbon dioxide. When muscle has a high level of carbon dioxide the horse becomes tired and cannot finish the race.

Additional key ingredients include Vitamin E which reduces oxidative stress. Selenium neutralise free radicals supporting the immune system. Branched chain Amino acids and Threonine supports muscle recovery essential for strengthening. Zinc and biotin support cellular repair and hoof growth. Available in 2L or 5L Plusvital racing syrup supports your horse in pursuit of their performance goals. 

For more information visit: www.plusvital.com

Why Choose Pro-Dosa in 2023?
As we all know, horsemen are responsible for the management of horses’ health, wellbeing, and fitness, to ensure they can perform to the best of their ability on the racetrack, but at the same time, a racing stable must be a profitable business and each horse must be economically viable for their owners.  As a result, in 2023, more than ever, horsemen must ensure they are getting the best possible value from the products they purchase.

Quite logically, horses under the added stress of hard work, transport, racing, competition, or illness have increased nutrient requirements.  Unlike people though, who often turn to food when under stress (think chocolate or chardonnay), horses tend to go off feed and drink less than they normally would.  Horses that fail to eat or drink well when travelling and racing will recover more slowly and will often perform below their best.  That is why many stables consider traditional, veterinary-administered, injectable pre-race/pre-travel treatments to be essential. Corrine Hills says “I originally developed Pro-Dosa BOOST, for horses in my own racetrack veterinary practice, as a more economical, less invasive, oral alternative to those treatments.”

Pro-Dosa BOOST is a complete, balanced multi-nutrient paste that I formulated to fill the gap between good daily nutrition and the increased requirements horses have when they are under stress. Pro-Dosa BOOST provides a practical way to deliver essential nutrients to horses that may not be eating or drinking enough, at those times, to support normal metabolism, performance, recovery, and heath.  

It contains a comprehensive range of water-soluble vitamins, trace elements, electrolytes, and amino acids in doses that reflect requirements established in scientific literature.  I have included them in readily usable forms, in good balance with each other, and in balance with the cofactors required for their absorption and function.”

Pro-Dosa International Ltd is GMP registered, demonstrating quality, safety, and security of the product from raw materials through to finished product.  Each batch of Pro-Dosa BOOST undergoes laboratory testing including complete quantitative analysis, demonstrating that each portion contains precisely what is on the label; microbial cultures, to ensure it is safe to feed; and Naturally Occurring Prohibited Substance screening.  

For more information contact: Email: info@pro-dosa.com Telephone: +64 27 238-8482

SPILLERS™ - Perform & Restore Mash

Racehorses need optimum nutrition to help them fulfil their full potential which is why SPILLERS™ has launched their new SPILLERS Perform & Restore Mash. The mash soaks super-fast in under 2 minutes providing convenience especially when travelling and is designed to be fed daily to support optimum condition and recovery.  It’s been formulated to assist hydration and complement the replacement of electrolytes post exercise.  Re-hydrating quickly is important particularly for horses in high intensity exercise as they rely heavily on muscle glycogen (stored glucose) for energy metabolism and although it takes up to 72 hours for glycogen stores to be fully restored, replenishment will be slower in dehydrated horses. 

SPILLERS Perform & Restore Mash is a low starch, molasses free blend of highly digestible fibre and oil to support digestive health and includes probiotic live yeast alongside prebiotic MOS and FOS.  The mash offers a high level of the essential amino acid lysine to support muscle tone and topline and includes branch chain amino acids to support muscle synthesis post exercise. What’s more, it supplies powerful antioxidants including vitamin C to support respiratory health and natural, bioavailable vitamin E to support immunity, muscle health and an athletic performance. 

Finally, SPILLERS Perform & Restore Mash includes an appetising apple aroma which is released when soaking to encourage even the fussiest of fussy feeders. 

All SPILLERS feeds are BETA NOPS approved.

For more information contact:  Website: www.spillers-feeds.com Care-Line number: 01908 226626

Fairfax - Better condition – better performance

Resolve to make 2023 the year you take a closer look at the exercise tack your horses wear on a daily basis – and follow the science when it comes to making choices that will improve performance.

Switching saddles could significantly improve a horse’s back health and movement, as well as reducing time off and vet bills this year. In scientific trials commonly-used exercise saddles (1/2 tree, 3/4 tree, and full tree) all caused areas of potentially detrimental high pressure. The Fairfax Exercise Saddle relieves pressure at a crucial point on the back (T13) so in gallop the hindleg is brought forward more and the quarters come further under the horse. The proven result is increased stride length and therefore more power.

If a horse is girthy or aggressive when being tacked up, consider the girth it wears on a daily basis. When straight girths were tested at gallop on a treadmill, the pressure was so high that the pressure mat was unable to record it. To achieve a significantly freer gallop with increased hindlimb extension, make the switch for 2023 to the Fairfax Race Exercise Girth which is shaped to avoid a peak pressure zone behind the elbow. It may also be an effective part of a multi-disciplinary approach in supporting horses with ulcers.

You could reduce or eliminate sore or rubbed withers this year by using a medical-grade closed-cell foam pad with a shaped central webbing spine. The Fairfax Race Exercise Pad provided superior pressure reduction without slipping in a pilot study where foam, gel and polyfill pads were compared. Gel pads increased pressure at the front of the saddle and those without a central spine (such as polyfill pads) slipped down onto the back at speed. In addition, using multiple polyfill pads does not relieve pressure – it increases bulk and instability. 

Scientists have proven that changing to a bridle that reduces pressure at the TMJ has a significant positive effect on the horse’s power, straightness and efficiency of stride. This is because the TMJ area is massively influential when it comes to locomotion. The Fairfax Race Bridle relieves pressure at the TMJ and other areas on the face resulting in improved front and hindleg range of motion. In addition, the Mexican grackle helps keep the bit stable in the mouth reducing sores and hanging associated with bridle pressure.

For more information visit: Fairfaxracing.com

Baileys New Race-Pro Cubes for the “Challenging Temperament”

Baileys’ new Race-Pro Cubes are a reduced starch alternative to oat-based racing feeds, delivering a highly palatable combination of slow and fast release energy to fuel racehorses of all types, in training, racing and recovery, throughout their season.  Ideal for horses whose temperament can be challenging when fed high starch mixes, these high fibre cubes support sustained performance and stamina, while also fueling speed.  

They contain a blend of highly digestible super fibres and oil, for slow release calories, with micronised wheat for readily available energy, and boosted antioxidant levels support muscle function and recovery.  Digest Plus prebiotic and a live probiotic yeast are included for optimum gut health, while a reduced starch content encourages a healthy gastric environment.  To complete the package, Race-Pro Cubes contain a full performance range of vitamins and minerals, including B vitamins, for healthy hoof growth, bone and tissue integrity and general well-being.

Where a low starch, high energy feed is required, for those prone to gastric ulcers for example, Baileys’ renowned Ease & Excel blend and Ease & Excel Cubes are proven to deliver, with starch levels of just 8%, yet Digestible Energy (DE) contents of 13MJ/kg and 12MJ/kg respectively.  Race-Pro Cubes provide 12MJ/kg of DE with a 17% starch level, compared to Racehorse Cubes (starch 26%/DE 13.5MJ/kg) and Racehorse Mix (starch 32%/DE 14MJ/kg).

For more information contact Baileys UK Racing Specialist, Will Humphries, on 07731 997580 or will@baileyshorsefeeds.co.uk

Outside of the UK, contact Export Manager, Mark Buchan, on  + 44 (0)7711 701565 or mark@baileyshorsefeeds.co.uk  www.baileyshorsefeeds.co.uk/racing

Bloomfields - Professional Raceline

This is the ultimate horsebox for young or difficult horses, stallions, & bloodstock.

Designed and precision engineered in the UK specifically for the transport of Bloodstock, the unmistakable & seamless Bloomfields Professional Raceline oozes class & elegance as well as its evident suitability for the industries demands.

A twist to our popular Professional model, which has been a market leading design used by amateurs and professionals throughout the world for over 15 years, we have designed with the involvement of industry experts to meet the needs of the end user, comfort and practicality for both the travelling staff and the horses.

The Professional Raceline is fitted with our one piece composite floor. Sliding partition, wall, door and roof padding is fitted as standard for superior comfort of the horse. Our woven, thermally bonded panels, doubled with our captive design are, in our opinion, the strongest on the market, but for extra peace of mind we also add an aluminium kick board throughout the horse area.

Bloomfields have designed and developed a slam locking system for the individual doors to each horse. Knowing that some travellers can be difficult, this gives super easy exit and entry to the grooms area without needing to bend down in front of the horses. Our Double catch slam locks make shutting the doors effortless and safe plus super easy access to each horse for easy preparation.

A very popular option for the Professional Raceline is the exquisite sliding partition. Absolutely indispensable for transporters and studs who carry mares and foals. Effortlessly glide the full height partition to the far wall with one hand and back to the centre point when required, meaning there is no need for more than one person to alter the stalls. Our 4 point locking system adds superior strength when in the central position.

The seamless under-sprung ramp gives a progressive lifting pivot meaning opening and closing the ramp is effortless. We never use gas rams, meaning the weight of the ramp will not change from the day of purchase.

What sets the Raceline apart from any other is the careful consideration into the practicality of the grooms area and how it can be a useful and resourceful place for storing everything from tack to veterinary medication and water barrels. Thorough research was undertaken to maximise the use of the space in the grooms area, with this in mind we have the option of a washable removable Hammock that is, as standard, mounted securely on the bulkhead. This allows travelling staff to relax without taking up essential weight or space.

One of the main factors considered when designing the Raceline was to put preventatives in place for cross contamination, particularly in the racing industry this is essential, So we have, as standard, supplied individual storage compartments for racing equipment & feed etc.

With safety in mind, believed to be the safest way to travel horses, The horses are separated by means of a full height, grilled partition, head divider, two full height grilled access doors, eliminating the need for a breast bar. The professional Raceline comes fully padded with an oversized rear door and dual reinforced glass fibre and Coat-X coated wheel arch covers. 

With an expansive list of optional extras to suit almost any requirement, including the 4.5t crewcab option in 2023, the Bloomfields Professional Raceline is the first and only form of 2 horse transportation you’ll need.

Our Professional Raceline is used throughout the world by professional transporters and riders, proving the strength and durability is second to none.

Contact us today to arrange a yard visit or for further details.

Telephone: 01558685117 / 07534849749 Email: BloomfieldsRaceline@Gmail.com Website: www.bloomfields.co/horsebox-models/raceline-professional

Probiotics as an alternative to antibiotics to reduce resistance in the gut

Article by Kerrie Kavanagh

The leading causes of horse mortality can be attributed to gastrointestinal diseases. Therefore, maintaining the balance of the gut microbiota and avoiding a shift in microbial populations can contribute to improved health status. The gut microbiota, however, can be influenced by countless dynamic events: diet, exercise, stress, illness, helminth infections, aging, environment and notably, antimicrobial therapy (antibiotics). These events can lead to gut dysbiosis—a fluctuation or disturbance in the population of microorganisms of the gut, which can contribute to a wide range of disease. The use of antibiotics in horses is thought to have one of the most notable effects on the gut microbiota (gut dysbiosis), which can lead to diseases such as colitis, colic and laminitis.

Antibiotics, which are antimicrobial agents active against bacteria, are important to equine medicine; and bacterial infections can be resolved quite successfully using antibiotics for antimicrobial therapy, but there are consequences to their use. An antimicrobial agent can be defined as a natural or synthetic substance that kills or inhibits the growth of microorganisms such as bacteria, fungi and algae. One of the consequences of antibiotic use is that of antibiotic-associated diarrhoea, which can contribute to poor performance in the horse and even mortality. In antimicrobial therapy, the target organism is not the only organism affected by the antimicrobial agent but also the commensal microbiota too (the normal flora of the equine gut). Antibiotics can promote fungal infections and resistant organisms and impede or even eliminate the more sensitive organisms; and they can have both short and long-term consequences on the gut microbiota composition and function. 

Research has indicated that antibiotic treatment may adversely affect metabolic function in the gut by decreasing protein expression responsible for biochemical pathways such as glycolysis, iron uptake, glutamate hydrolysis and possibly even more metabolic functions. The use of antimicrobial drugs directly impacts and possibly contributes to the most notable effect on the gut microbiota of the host, leading to gut dysbiosis; and certain antibiotics can have further-reaching consequences on the microbiota than others. The type of antibiotic and mode of action (bacteriostatic versus bactericidal) will differ in their influences on the gut microbiota composition, e.g., clindamycin operates a bacteriostatic mode of action by inhibiting protein synthesis and exerts a larger impact on the gut microbiota compared to other antimicrobials. These influential consequences that are imparted by the antimicrobial agent are relatively yet to be elucidated and may result in the manifestation of illness or conditions later in life. For example, the development of asthma in humans has been linked to antibiotic treatment in early childhood as a result of bacterial infections. It may yield interesting results if researchers were to examine the gut microbiome of horses suffering from chronic obstructive pulmonary disease (COPD) and other chronic respiratory illnesses and to establish if there is indeed a link with antibiotic therapy used in horses from an early age. 

In comparison to the vast wealth of human studies conducted so far, the volume of equine studies falls disappointingly far behind, but that is changing as researchers focus their interest on developing and filling this gap of knowledge. One such study which examined the effect of antibiotic use on the equine gastrointestinal tract, demonstrated a significant reduction in culturable cellulolytic bacteria (>99%) from equine faeces during the administration period of trimethoprim sulfadiazine and ceftiofur in a study comparing responses to antibiotic challenge. That reduction was still evident at the end of the withdrawal period when compared to the control group. In other words, there was a significant reduction in the ‘normal’ bacteria of the gut. The ability of antibiotics to modulate the gut microbiota was evidenced by the proliferation of pathogenic Salmonella and Clostridia difficile (commonly associated with diarrhoea in horses) in the antibiotic challenged horses. This trend of reduction in cellulolytic bacteria associated with antibiotic use was also mirrored in a relatively recent study conducted in 2019, where a short-term reduction in culturable cellulolytic bacteria was combined with a progressive increase in amylolytic bacteria. The heavy reliance on cellulolytic bacteria in the role of equine digestion (without these types of bacteria the horse cannot break down their food) may, therefore, adversely affect the dietary energy available from forage during antimicrobial therapy and may therefore impact performance.

Another study that compared the effect of penicillin, ceftiofur and trimethoprim sulfadiazine (TMS) on the gut microbiota in horses using next-generation sequencing showed that TMS had the most profound impact on the microbiota, in particular the phylum Verrucomicrobia. This same study also reported a significant decrease in bacterial richness and diversity of the faecal microbiota. A reduction in bacterial diversity is certainly a trend that is commonly seen in gastrointestinal disease in horses. The restoration of the normal gut microbiota after completion of antibiotic treatment can take up to 40 days, but the organisational structure of the bacterial populations can take many years to re-establish the original structure map that was laid out in the gut pre-antibiotic treatment. 

The equine studies certainly show similarities to the human studies, indicating the consequences of antibiotics that can be seen across more than one species. Human studies have reported long-term consequences of antibiotic treatment on the human microbiota. One such human study investigated a 7-day clindamycin treatment and monitored the patients for two years. The impact on the human microbiota remained evident two years post-treatment, where a reduction in bacterial diversity and detection of high-resistance to clindamycin were detected. 

Interestingly, no resistant clones were detected in the control group over the two-year sampling period. Another study focusing on the effects of antibiotic treatment for Helicobacter pylori showed findings mirrored in similar studies of that field. The findings demonstrated the rapidly reducing bacterial diversity (one week) after antibiotic treatment and found that disturbances in the microbiota and high levels of macrolide resistance were evident four years post-treatment. Human studies may predict that equine studies will find similar trends with equine antimicrobial therapy. These studies highlight the impact of antibiotic use and the long-term persistence of antibiotic resistance remaining in the intestinal microbiome, which is a concern for both humans and animals. 

Antibiotics can lead to the selectivity and proliferation of resistant bacteria, which is evidenced by the long-term effects observed on the gut microbiota harbouring drug-resistant encoded genes. Horizontal gene transfer (HGT) commonly occurs in the gut (can be up to 25 times more likely to occur in the gut than in other environments). HGT can be attributed to the close proximity of the microbiota in the gut, allowing the transfer of genetic material via routes such as plasmids and conjugation; in other words, the bacteria in the gut have developed a pathway to transfer antibiotic resistant genes from one generation to another. Resistance to antibiotics is now a global issue for the treatment of many diseases. 

With the unfavourable association tied to Clostridium difficile infections (CDI) and the onset of colitis particularly in mature horses treated with β-lactam antibiotics (commonly used for equine infections), the incidences in which antimicrobial therapy is considered should be minimised and only used if entirely necessary. The use of broad-spectrum antibiotics in recurrent presentations of symptoms of disease such as urinary tract infections in humans or diarrhoea as a result of CDI in both humans and horses is promoting drug resistance.

The antibiotics, by disrupting the gut microbiota (which act as a defence against the establishment and proliferation of such pathogenic bacteria) are allowing the opportunity of growth for these multi-resistant microorganisms such as C. difficile, vancomycin-resistant enterococci (VRE), and multi-resistant Staphylococcus aureus (MRSA). The organism C. difficile and its antibiotic resistance has been demonstrated in the treatment of CDI for both humans and animals. The introduction of vancomycin (a glycopeptide antibiotic) in 1959 for the control of CDI remained effective until the 1990s when a more virulent form of C. difficile emerged. This new form of C. difficile with reported broad-spectrum antibiotic resistance resulted in chronic conditions and increased human mortality. C. difficile is most noted with human hospital-acquired infections. C. difficile BI/NAP1/027 has been shown to have resistance to fluoroquinolone antibiotics, moxifloxacin and gatifloxacin, which was not seen in historical genotypes. As C. difficile infections are found to cause gastrointestinal disease in horses as well as humans, this is certainly of concern.

Alternative therapies to antibiotic therapy to restore or modulate the gut microbiome after a gut dysbiosis event could be considered in certain circumstances where antibiotics are no longer effective (e.g., CDI), nor may they not be the best course (presence of Extended-spectrum -β-lactamase producing (ESBL) organisms) nor essential for example, when the diagnosis of the bacterial cause is uncertain. The rationale to using probiotic treatment along with antimicrobial treatment is that the antibiotic will target the pathogenic bacteria (e.g., C. difficile) and also the commensal microbiota of the gut, but the probiotic bacteria will help to re-establish the intestinal microbiota and in-turn prevent the re-growth of the pathogenic bacteria in the case or residual spores of C. difficile surviving the antibiotic treatment. Alternative therapies such as faecal microbiome transplant (FMT) or probiotic solutions can reduce the risk of proliferation of antibiotic-resistant bacteria and also have fewer implications on the gut microbiome as evidenced by antibiotic use. 

Probiotics have been defined by the Food and Agricultural Organisation (FAO) and the World Health Organisation (WHO) as “live non-pathogenic microorganisms that, when administered in adequate amounts, confer a health benefit on the host”. The word ‘probiotic’ is Greek in origin, meaning, ‘for life’; and the term was coined by Ferdinand Vergin in 1954. While the mechanisms of action of probiotics are complex and require a deeper knowledge of the modulations of the gastrointestinal microbiota, and the health benefits due to their use are the subject of some debate, there is no doubt that probiotics are considered by many as a vital resource to human and animal health.   

The use of probiotics in animal production, particularly in intensive swine and poultry production, has increased in recent years, primarily as an alternative to the use of antimicrobials in the prevention of disease. The problem of antibiotic-resistance and antimicrobial residues in food-producing animals (the horse is considered a food-producing animal), as a result of historical antibiotic use with the corresponding reduction in antibiotic efficacy in humans, leads to having to look at more sustainable options such as probiotic use to combat disease. Probiotics in horses are predominantly used as a treatment modality in the gastrointestinal microbial populations to combat illnesses such as diarrhoea—to prevent diarrhoea (particularly in foals) or help improve digestibility.  Shifts or fluctuations in the microbial populations of the equine gastrointestinal tract have been associated with diseases such as laminitis and colic.  

Gut dysbiosis, as mentioned previously is, a fluctuation or disturbance in the population of microorganisms of the gut is now being recognised as a cause of a wide range of gastrointestinal diseases; and in horses, it is one of the leading causes of mortality. The ability of probiotics in conferring health benefits to the host can occur via several different mechanisms: 1) inhibiting pathogen colonisation in the gut by producing antimicrobial metabolites or by competitive exclusion by adhering to the intestinal mucosa preventing pathogenic bacteria attachment by improving the function and structure; 2) protecting or restabilising the commensal gut microbiota; 3) protecting the intestinal epithelial barrier; 4) by inducing an immune response.

It is known that there is a wealth of factors that will adversely affect the gut microbiome, antibiotics, disease, diet, stress, age and environment are some of these compounding contributors. To mirror one researcher’s words echoing from an era where antibiotics were used as growth promoters in the animal industry, “The use of probiotic supplements seeks to repair these deficiencies. It is, therefore, not creating anything that would not be present under natural conditions, but it is merely restoring the flora to its full protective capacity”. In the case of using concurrent antibiotic and probiotic treatment, this strategic tweaking of the microbiota could be used as a tool to prevent further disease consequence and perhaps help improve performance in the horse.

The benefits of probiotic use in horses have not been investigated extensively but as mentioned previously, they are now being focused upon by researchers in the equine field. The most common bacterial strains used in equine probiotic products are Lactobacillus, Bifidobacterium, Streptococcus, Enterococcus, Bacillus and yeast strains of Saccharomyces. Lactobacillus, Bifidobacterium and Enterococcus strains typically account for less than 1% of the microbiota large gastrointestinal populations.

Regulation is lacking regarding labelling of probiotic products, often not displaying content with clarification and quality control (such as confirmed viability of strain[s]) not excised with over-the-counter probiotic products. There is evidence to suggest that host-adapted strains of bacteria and fungi enjoy a fitness advantage in the gut of humans and animals.  Therefore, there may be an advantage in using the individual animal’s own bacteria as potential probiotics. Probiotics and antibiotics used concurrently could be the way to minimise the introduction of antibiotic-resistant bacterial strains in the gut, and in turn, protect future antibiotic efficacy. 

Feeding from the sales ring to racecourse

Author - Cath Dunnett

Horseracing’s international sales rings can perhaps be regarded or compared with the professional show circuit. To achieve optimum interest and price, youngsters not only need to be genetically well endowed but must be appealing to the buyers eye. Youngsters need to be in good body condition, ideally fit but not fat with good muscle tone, sufficient topline and a gleaming healthy coat. However the overall ‘picture’ desirable for the sales ring may not be the most appropriate for full training and competitive racing, and so trainers may find themselves needing to resculpture horses in their early days of training.  

Yearling Prep

Yearlings are prepared (‘prepped’) intensively for the sales ring. Whilst most yearling prep regimes will incorporate some exercise, this tends to be mostly walking; and yearlings may lack the established and better developed musculature needed for racing. There is also a high reliance on feeding to deliver the ‘sales ring look’.

Prep regimes are often short lived and designed to increase weight and condition relatively quickly, and to produce gleaming coat condition and topline—the latter of which can therefore be based on deposition of adipose tissue or fat, rather than muscle development or hypertrophy.

A prep period typically involves feeding a large amount of high energy, starch-rich feed over a relatively short period of time, typically 6-8 weeks. Research tells us that this prep period is likely to be one of the high risk times for non-glandular gastric ulcers to develop. Large starch-rich feeds, confinement, increased periods of stress and restricted access to pasture or forage are all significant risk factors for gastric ulcers.

Some yearlings will inevitably arrive at the trainer or pre-trainers yard with pre-existing non glandular ulcers, which may require veterinary treatment, or at the very least a sympathetic high forage, low-starch and sugar-based ration for early training. It may be controversial to suggest, but a longer slower period of prep for sales would perhaps allow for a greater contribution from exercise to build muscle, combined with a less intense feeding regime. However, time and economics probably contain too much deviation from the existing model. 

Bone Density

Yearlings that move through from studs to sales prep and then into a training yard undergo a very big change in their feed and management that is worthy of consideration. A stud regime and diet are very different to both sales prep and pre-training, in terms of composition and environment. At stud, these young animals spend a large portion of their day at pasture, with a generally small amount of top up feed or balancers to complement the grazing.

A diet, which is typically high in pasture and forage and low in cereals, allows minerals such as calcium to be firmly sequestered in bone, maintaining bone density. In horses on good pasture, this is aided by the high vitamin K1 content of pasture, which is needed to activate osteocalcin involved in the sequestration of calcium in bone. In contrast, with a high-cereal, low-forage prep or pre-training diet—as a result of quite complicated homeostatic mechanisms involving hormones such as parathyroid hormone—calcium can become relatively more mobilised from bone. The characteristic drop in bone density commonly seen in racehorses in the first 60-90 days of training can be the physical result of this phenomenon.  

Forage First

Yearlings may come into training on the larger side of perfect for racing; and so it may, at first glance, seem counterintuitive to feed plenty of forage at this time. However, in early training it is a worthwhile exercise, as it establishes good eating habits.

Horses in training often self limit their forage intake, as training progresses and appetite is reduced, which can contribute to problems including inability to maintain condition, gastric ulcers and tying up if the forage intake drops too low. Better to start from a slightly higher intake early on, than to find a horse on a forage knife edge later in training.

Forage, whether hay or haylage, contributes significantly to energy and electrolyte intake and is a particularly rich source of potassium—an important electrolyte for overall metabolism and muscle function. Leguminous forage such as alfalfa/lucerne is highly digestible and so has a reduced effect on gut fill (hay belly). Alfalfa is equally rich in calcium to help buffer the natural mobilisation and loss of calcium from bone during early training.

A couple of kilograms of alfalfa per day complements a more traditional less digestible hay such as Timothy. The added advantage of feeding a decent amount of forage is that the level of concentrate feed needed will also be reduced. Forage provides energy mainly from fibre and so is not generally associated with excitability, with the energy provided being colloquially known as slow-release energy.

A decent amount of forage for a horse in training is about 1.5% of bodyweight; so for a 500kg horse, that’s about 7-8kg or 4 typical slices. For haylage, this needs to be slightly higher to account for its higher water content.

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Nutrition - antioxidants - their role in racing - is there merit in specifically supplementing antioxidants to enhance performance?

By Catherine Rudenko

Antioxidants are substances that slow down damage to organisms created by the presence of oxygen. The need for antioxidants is always there, in all species, increasing as exercise intensity and duration increase. Is there merit in specifically supplementing antioxidants to enhance performance?

The nature of antioxidants

There are many forms of antioxidants naturally present within the body and supplied through the diet. One key feature of antioxidants is that they are ‘team players’. No one antioxidant alone can maintain the system, and some will only function in the presence of another antioxidant.

The role of an antioxidant is to keep reactive oxygen species (ROS) or free-radicals created in the presence of oxygen at an optimum level. Oxygen is required for life, it is always present, but as an element, it is highly reactive and so can also have an adverse effect on the body. The reactivity of oxygen in the body produces ROS which cause damage to cellular components such as DNA, proteins and lipids of cell membranes. Some ROS also have useful cellular functions, and so the purpose of antioxidants is not to eliminate ROS altogether but to maintain a healthy balance. In general, antioxidants operate in two ways: either preventing the formation of an ROS or removing it before it can cause damage to a cell component.

Sources of antioxidants

There are multiple sources of antioxidants including vitamins, enzymes and nutrient derivatives. Other nutrients such as minerals, whilst not having antioxidant properties, are also involved as their presence is required for the functioning of antioxidant enzymes. Two key examples are zinc and selenium.

As with many body systems, the ideal healthy balance can often go awry. When the level of ROS present overwhelms the capacity of antioxidants present, the body experiences oxidative stress. There are three main reasons for a horse in training experiencing oxidative stress:

• Increased exposure to oxidants from the environment

• An imbalance or shortage in supply of antioxidants

• Increased production of ROS within the body from increased oxygen metabolism during exercise

Oxidative stress is of concern as it can exaggerate inflammatory response and may be detrimental to the normal healing of affected tissues. Oxidative stress during strenuous exercise, such as galloping or endurance, is typically associated with muscle membrane leakage and microtrauma to the muscle. Oxidative stress is now understood to play a role in previously unexplained poor performance.

Dietary antioxidants photo: horse eating?

Given the demands of training and the regularity of intense exercise and racing itself, the use of dietary antioxidants is an important consideration. As antioxidants are generally best considered as a cocktail, it is necessary to give consideration to provision of nutrients and their derivatives across the total daily diet.

The majority of racing feeds will be formulated to provide a good cocktail of basic antioxidants or their supporting minerals. All feeds will contain vitamin E, selenium and zinc for example. Some, but not all, feeds will also provide vitamin C. The source of these nutrients may also differ; for example, some feeds will contain chelated zinc or organic selenium, which offer improved availability. The source of vitamin E will also vary—the majority being provided as synthetic vitamin E; but some will include natural sources of vitamin E, which is more effective.

TOP: Oxidative stress is now understood to play a role in previously unexplained poor performance.

Once a good base diet is in place, consideration for strategic use of individual antioxidants may then be warranted to further enhance the capacity of the body to mitigate the effects of ROS on the muscle. Three popular and commonly used antioxidants are vitamin E, vitamin C and more recently coenzyme Q10.

Vitamin E

As a lipid-soluble antioxidant, vitamin E provides defence against ROS in cells, playing an important role in maintaining integrity of cell membranes. Vitamin E is the most commonly supplemented antioxidant. There are established recommended daily intakes for vitamin E, typically 1000 IU per day for a horse in training; however, further supplementation beyond the basic nutritional requirement can yield benefits. Modern race horse feeds are well fortified—the majority providing upwards of 300 IU/kg, resulting in an average daily intake of over 2000 IU/day.

Intakes of above the base rate have been investigated for their effect on CK (creatine kinase) and AST (aspartate aminotransferase)—two markers of muscle damage. One such study used endurance horses whereby intakes ranged from 1150 IU up to 4750 IU per day. Elevated intakes of vitamin E correlated with lower levels of CK and AST suggest that vitamin E can affect muscle membrane permeability and injury to muscle during exercise.

As a guide to improving antioxidant capacity, an intake of up to 5000 IU per day would be appropriate for a horse in training. Vitamin E intake is influenced by the level of fats fed in the diet; and where additional oils are added, further vitamin intake E is required, as vitamin E will be utilised in stabilising the oil itself. Fats fed in a dry format, such as extruded rice bran, are normally fortified with vitamin E for this reason and do not require further supplementation.

Vitamin E is available in feeds and supplements in two forms: synthetic or natural. The natural form, d-alpha-tocopherol, is made up of a single isomer (chemical unit). The synthetic form, dl-alpha-tocopherol, is made up of eight different isomers—only one of which is molecularly the equivalent of natural vitamin E. The dose rate required to increase serum vitamin E levels in horses is lower for natural E than synthetic vitamin E.

The increased bioavailability of natural vitamin E has led to further research in comparing this source against synthetic vitamin E for efficacy against oxidative stress and physical gait changes. The study used 3 diets: a control diet with the standard recommended intake of 1000 IU/day provided by synthetic vitamin E; a higher intake synthetic vitamin E diet of 4000 IU/day; and a high intake of natural vitamin E at 4000 IU/day. The study lasted for six weeks and measured serum levels of vitamin E at various time points along with markers of oxidative stress, CK and AST levels, and gait analysis.

The key findings:

All diets increased serum vitamin E over time; however, the increase was not significant in the diet, providing only 1000 IU/day of synthetic vitamin E. The greatest difference in serum vitamin E was seen in the natural vitamin E diet where levels increased by 77.25% from day one to the last time point.

Oxidative stress was measured through multiple tests including oxidation of lipids (TBARS). Horses supplemented with natural E had lower levels of lipid oxidation markers than both synthetically supplemented horses at the second exercise test, which occurred after six weeks of fitness training.

AST levels were lower within the two hours post exercise of natural E supplemented horses compared to synthetic vitamin E horses; however, by 24 hours, the difference was no longer significant. There was no noted significant effect on CK.

Gait analysis before and after exercise showed better movement of horses that were supplemented with natural vitamin E. These horses experienced less of a reduction in their stride duration post exercise, potentially indicating less muscle soreness due to less oxidative stress.

As vitamin E is well proven to be an effective antioxidant, it may be tempting to think that ‘more is better’; however, as with all nutrients, there is a safety limit to consider. Current research indicates that supplementing at 10 times the base level—an intake of 10,000 IU/day—may result in poor bone mineralisation and impair beta-carotene (vitamin A) absorption. An intake of 4000-5000 IU/day based on the research above and other studies would appear effective whilst also being well below the presumed safety limit.

Vitamin C

Ordinarily horses can manufacture adequate vitamin C within the body, unlike humans that require direct supplementation. Additional vitamin C is required and often recommended when the body is challenged through disease or periods of stress. …

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The importance of good nutrition and its bearing on mental health

By Lissa Oliver

Unique to the racing industry is the daily need for staff to meet required maximum weights. Many in racing already believe they understand nutrition and the best methods to make weight, using tried and tested practices that have been in common use for decades. The perceived success of such practices leads to an attitude of ‘it works for me’ and a reluctance to change or adopt new suggestions, and few consider the future consequences on health in later years.

Dehydrating and starvation to make weight is commonplace, and long periods in saunas and salt baths, laxatives and self-induced vomiting are familiar practices. The health implications associated with these include poor bone density, hormonal issues and impaired mood profile. Despite increased awareness of these problems, they remain as common globally as they were thirty years ago.

To help address this, the UK based Racing Foundation awarded a grant of just over £200,000 to support a ground-breaking, nutritional intervention programme developed over three years by a specialist team at the Research Institute of Sport and Exercise Sciences at Liverpool John Moores University. The team is led by former jockey, Dr George Wilson, and includes the head of nutrition for cycling’s Team Sky, Dr James Morton, and Daniel Martin, a doctoral researcher and high-performance nutritionist for the Professional Jockeys Association.

Dr Wilson has already spent seven years (part-funded by the Sheikh Mansoor Racing Festival) researching the serious health implications of extreme weight-making practises in jockeys and has designed healthier, alternative weight-making programmes. In addition to offering the facilities at the University to measure bone and body composition, hydration, metabolism and provide strength and fitness assessments, he also works with racing organisations to provide workshops, tests, presentations and bespoke advice. He is in the ideal situation to conduct research into the health issues faced by racing staff, having ridden as a National Hunt jockey in his younger days.

“For my first ride as a conditional jockey at Southwell in 1985, I lost a stone in five days to make 10st (63.50 kg) minimum weight, felt awful and, given the occupational risks, I shouldn’t have been near a horse, let alone riding in a race,” he reflects on his experience. He later rode as an amateur mostly in point-to-points and hunter chases when weight became a problem. “Having ridden over jumps, I fully empathise with staff and understand the need for, and risks from, dehydration and starvation. Riding out stable staff are weighed in some yards and most vacancies are advertised with a maximum weight, so making weight is not just a problem for jockeys but also for a lot of racing staff.

“I was aware that not a lot had changed since my own time in yards in the 1980s and 1990s and so I decided to do my doctorate in the effects of common weight-making practices such as dehydration and nutrition (or lack of!). In 2009 I started my first research and have now had 11 papers published.”

Currently, Dr Wilson is studying the effects of diet, dehydration and bone health of jockeys, but, as he recognises, comparisons of bone density between standard 12st athletes and 9st, (57.15 kg), jockeys may have potential flaws given jockeys are an atypical population, being much smaller athletes. Furthermore, unlike other athletes, jockeys don’t tend to perform substantial hard surface training that helps maintain healthy bone metabolism.

Assisting Dr Wilson is Daniel Martin, and their paper, Qualitative Research in Sport, Exercise and Health (31 August 2017), is the first body of research to investigate the opinions and practices of racehorse trainers in relation to rider welfare. Disappointingly for the researchers, from over 400 invitations, only five trainers expressed an interest to take part, something that certainly needs addressing.

A reluctance to face up to industry problems isn’t new and is not confined to trainers. “When I first went to the British racing industry authorities and said I wanted to do this, they originally didn’t offer any help,” he reveals. “There appeared to be a reluctance to accept that the current services and advice to help riders, particularly with weight-management, were clearly not working. Therefore, I just ‘kicked on’ with my research, and because jockeys had not received the sports science support in the past, they flocked to LJMU to undergo the testing and receive bespoke weight-management programmes.

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“Thankfully, now everyone is aware of the issues and have embraced the research findings on healthier weight-management practices, and it appears we are all singing from the same hymn sheet. Indeed, Dr Jerry Hill, the Chief Medical Advisor at the British Horseracing Authority, is a collaborator on some of my recent published research and we have some other research projects we are currently working on together.”

Even so, it is an industry culturally-driven and based on the shared knowledge and experience of its senior professionals, which can represent an obstacle to Dr Wilson and his team when some of that knowledge is outdated and incorrect. As Martin explains within one of the published papers, “If apprentice and conditional jockeys can carry some knowledge of evidence-based practices and the dangers of traditional methods into their early careers, there will be less of a reliance on seeking advice from senior jockeys. Similarly, over time the ‘new’ practices will hopefully supersede the current archaic medley of dehydrative methods.”

It certainly behoves trainers to ensure that younger staff members are set good examples and it isn’t asking too much of their time or level of expertise to provide suitable meals, in yards where catering is offered. Where meals are not provided, posters and literature should be made available to display in the yard to help encourage awareness of a good diet.

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From Fertility to Foal: considerations for digestive tract health

By Emma Hardy, PhD

The success or failure of any breeding program is dependent on the nutritional status and digestive tract health of foals, mares, and stallions alike. Although this aspect of the operation is often overlooked, it is only by ensuring that these considerations are optimised that foals are given the best chance to survive and thrive, from birth through weaning and on to sale.   

A weighty issue

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There exists surprisingly little research surrounding the nutrient requirements of the breeding stallion. This may be in part complicated by the great variation in activity; some stallions may serve several mares a day during peak periods in the breeding season, while others may serve only that number in a year. Other influencing factors may include temperament, management routine, and competitive activities. However, it is generally agreed that energy demands are indeed above maintenance levels, and according to various National Research Council studies it has been suggested that active stallions require approximately a third more digestible energy than their non-breeding, sedentary counterparts.  

Research in other species has shown that a body condition that deviates greatly from the ideal can be associated with an increased risk of infertility (Nguyen et al. 2009). Nutritional content is also of great importance, with zinc and omega-3 fatty acids playing important roles in sperm motility, mobility, and viability.

Extremes in body weight and condition can also affect the fertility of broodmares. Low levels of body fat in mares can inhibit or delay ovarian activity, and obesity is often associated with insulin resistance (equine metabolic syndrome, or EMS), which can also disrupt cyclicity. Gentry et al. (2002) found that mares with a body score of 3-3.5 demonstrated a longer anaestrus than mares with a good body score (eg., 5) (Henneke et al. 1983) and was accompanied by lower plasma leptin, prolactin, and insulin-like growth factors.

It would therefore be sensible to carefully manage the weight and condition of both broodmares and stallions to optimise breeding potential.

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Safely improving body condition and weight

For horses struggling to maintain ideal body condition it is important to assess forage intake and quality, and to also increase concentrates. Energy-dense grains and fats are often employed in these situations; however, caution must be taken to avoid the digestive tract issues these can cause.

Adding fat-fortified feeds to the diet, or top dressing fats or oils, can be an effective way to increase caloric intake. However, oils can pose a palatability issue. For a significant caloric contribution, somewhere between 200-500 ml/day of vegetable oil would be required. This would also increase the need for additional vitamin E and selenium to counteract the greater antioxidant need of a horse on such levels of supplementation.

The horse is naturally limited in its capacity to digest large volumes of starch, so concentrations should be limited to about 2g starch/kg body weight per meal, which equates to 0.2% starch or 1.4kgs of grain per meal. Anything over this risks starch bypass through to the large intestine, which can cause a bacterial inversion and ultimately a range of issues from poor feed absorption and inflammation to colic and laminitis.    

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The Positive and Negative Effects of Oil in Equine Nutrition

Published in European Trainer, January - March 2018, issue 60.

Oil is a regular addition to modern racing diets, either by feeding a high oil-containing racing feed or through extra addition of liquid vegetable oil. Research over the years has shown that oil is palatable to horses and digested very well, and that there is little difference in digestibility between the main types of vegetable-based oils used.

Oil that is integral to feed ingredients, such as that found in rice bran, linseed, naked oats, soya, etc., may have a marginally lower digestibility, as this will depend on how digestible the encapsulating matrix is to the horse. However, in the main both free oil and integral oil is well tolerated and digested in horses.  

In a natural environment, horses can easily consume between 2-3% of their body weight as dry matter from pasture. Oil has always been a natural part of the horse's diet, as grass contains about 2-3%, which may seem low but can provide the equivalent of 200-400mls of oil per day. Other forages, such as hay, haylage, and chaff, will also contain oil at a similar level on a dry matter basis.  

Horses can tolerate up to 20-25% of their total energy intake coming from oil, and this has been exploited successfully....

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Does nutrition factor in injury, repair and recovery?

First published in European Trainer issue 58 - July - September 2017

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Lost training days through injury or infection are problematic for trainers, both practically and commercially. It is a stark fact that 50% of thoroughbred foals, bred to race, may never reach the racecourse.

Lost training days through injury or infection are problematic for trainers, both practically and commercially. It is a stark fact that 50% of thoroughbred foals, bred to race, may never reach the racecourse.  In young thoroughbreds, musculoskeletal problems have been cited as the most common reason for failure to race and this appears to continue to be a major issue for horses in training.  

An early study carried out in 1985 in the UK reported that lameness was the single biggest contributor to lost days of training, and subsequent research 20 years later found that this was still the case, with stress fractures, which involve normal bone being exposed to abnormal stress, being cited as a significant underlying cause.  Perhaps not surprisingly, two-year-olds were more susceptible to injury than three-year-olds.  Whilst there are of course many other reasons – including muscular issues such as tying up, respiratory problems, and viral infection – why horses may fail to train, in this survey medical issues accounted for only 5% of the total training days lost.

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The benefits of salt

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First published in European Trainer issue 57 - April '17 - June '17

Feeding fibre to racehorses

Links to read:

North American version: issue 30 Fall/Winter 2013

European version: issue 43 Autumn 2013

Hydroponic feeding - the pros and cons of this resurging concept

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Sports nutrition - Horses and humans. What parallels can we draw?

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European Trainer - issue 33 - Spring 2011)

Racehorse Nutrition - Vitamin K – the forgotten vitamin

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(European Trainer - issue 32 - Winter 2010)

Can nutrition give horses that "first class" travel experience?

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(European Trainer - issue 31 - Autumn 2010)

Tying up some loose ends on rhabdomyolysis - can nutrition help treat or prevent tying up?

A horse with raised muscle enzymes is always a cause for concern for trainers, whether it is a single isolated incident or a regular occurrence.

There has been a slow but steady increase in our knowledge of this disease or syndrome, which in more recent years has been helped by the application of genetic-based tests for some forms. An increase in our understanding of the metabolic basis for the syndrome is imperative and will help us to better manage these horses in terms of nutrition and training.

Catherine Dunnett (European Trainer - issue 29 - Spring 2010)

Picky Eaters - a common problem in horses in training

Poor appetite in horses in training is not uncommon, whether this is a transient problem following racing, or, more regularly, during training in particular horses. In some situations, ‘failure to clean up’ may simply be explained by horses being offered more feed than they require and so they are being overfed, whilst in other instances, where it is accompanied with poor condition, the causes may be more complicated. Certainly, physiological mechanisms exist in horses to match energy and nutrient intake to daily requirements and these systems form the basis for self regulation of feed intake in horses in the wild or at grass.

Catherine Dunnett (14 October 2008 - Issue Number: 10)

The Role Vitamins Play in the Diet

Vitamins are a key part of the diet for racehorses and although the clinical signs associated with an overt deficiency or excess of one vitamin or another are rare, we should not presume that the level of vitamins provided in the diet is optimized for performance. Horses are, generally speaking, quite tolerant of sub-clinical deficiency or excess with regards to vitamins, and the margin of acceptable intake to prevent health issues is therefore relatively wide in most cases. However, maintenance of health is a separate issue compared to optimal performance, which is the ultimate target for horses in training.

Catherine Dunnett
 (14 October 2008 - Issue Number: 10)